Instrumentation

The Facility provides mass spectrometry service in support of analyte identification/verification, structural elucidation, and quantitation of individual compounds and complex mixtures for the University of Missouri and outside users (please see our Services and Fees).

LC/MS work in the Mass Spectrometry Facility centers around our Thermo LTQ linear ion trap. This instrument is equipped with an electrospray (ESI) source which can operate in positive and negative ion modes. Samples can be introduced by direct infusion or following separation using high performance liquid chromatography. Both qualitative and quantitative analyses are available by using full scan, single ion or selected reaction monitoring. A variety of tandem mass spectrometry experiments can be performed with ions produced by ESI.

In cooperation with the MU Proteomics Center, other mass spec services may be available including accurate mass determination.

Current and future users should note: before planning use of the facility for research, analyses, or before applying for grants, please consult with us about your requirements and time needs. This will permit us to best match your goals with available methods.